Program Agenda 2018

2018 Annual William C. Wood Research Symposium
Department of Surgery
Emory University School of Medicine

April 26, 2018

Emory University Hospital Auditorium

Schedule of Events

8:00 AM

Introduction of Keynote Speaker by Nicole Turgeon, MD

Keynote Lecture
Advancing Immunotherapy in Breast Cancer: A Surgeon Scientist's Adventure
Presented by Elizabeth A. Mittendorf, MD, PhD
Robert and Karen Hale Distinguished Chair in Surgical Oncology, Brigham and Women's Hospital
– Director of Surgical Research, Dana-Farber/Brigham and Women's Cancer Center Breast Program
– Director, Breast Immuno-Oncology Program, Dana-Farber Cancer Institute
– Co-Director, Breast Cancer Clinical Research Program, Dana-Farber Cancer Institute

8:05 AM

Welcome Remarks by Nicole Turgeon, MD

Moderators: Scott Davis, MD, and William Kitchens, MD, PhD

8:15 AM

Molecular Imaging of Colonic Neoplasms with Novel Receptor Targeted and NIR-Dye-Labeled Nanoparticles, Abstract #11, Page 8
Mohammed Raheel Jajja

8:25 AM

The Conundrum of <2 cm Pancreatic Neuroendocrine Tumors: A Preoperative Risk Score to Predict Lymph Node Metastases and Guide Surgical Management, Abstract #7, Page 9
Alexandra Lopez-Aguiar

8:35 AM

The Balance of CD28 and CTLA4 Signals Controls TIGIT Expression on Antigen-Specific CD4+ Effector T Cells, Abstract #18, Page 10
Sonia Laurie

8:45 AM

A Novel Classification System for Adrenocortical Carcinoma: Proposal from the US Adrenocortical Carcinoma Study Group, Abstract #12, Page 11
Sonia Laurie

8:55 AM

FcyRIIB is a Novel Coinhibitory Molecule on Effector CD8+ T Cells, Abstract #26, Page 13
Anna Morris

9:55 AM

(poster presenters and judges transition to classrooms)

10:00 AM

Moderators: Lily Yang, MD, PhD, and Mehul Raval, MD, MS

10:05 AM

Parent Reported Quality of Life Outcomes in Children with Congenital Diaphragmatic Hernia, Abstract #15, Page 14
Jill Morsberger

10:15 AM

CD28 Directed Immunotherapy is More Potent Than Belatacept in a Pig-to-Non-Human Primate Renal Xenotransplant Model, Abstract #9, Page 16
Steven C. Kim

10:25 AM

Using TAMIS to Expand Size and Circumference Criteria For Rectal Lesions, Abstract #38, Page 17
Adekemi Egunsola

10:35 AM

Anti-TIGIT Antibody Reverses Immune Suppresion and Improves Survival in a Model of Cancer and Sepsis, Abstract #54, Page 18
Wenxiao Zhang

10:45 AM

A Multi-Institutional Analysis of Patients Undergoing Hybrid Coronary Revascularization for Multivessel Coronary Artery Disease, Abstract #55, Page 19
Nnaemeka Ndubisi

10:55 AM

Closing Remarks and Awards Presentation by Nicole Turgeon, MD

11:00 AM

Announcement of the Symposium Winners and Adjourn
(Winners are asked to remain in the auditorium for group photo)

11:10 AM-
12:00 PM

Presenters Luncheon
All presenters are invited to join Dr. Elizabeth A. Mittendorf and the Surgery Research Advisory Committee in the Whitehead Room, EUH, 2nd Floor, Administration Wing

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Poster Session

Posters – Basic Science

Poster #16

Polycaprolactone-Chitosan Nanofibers Electrospun On Decellularized Bovine Pericardium As a Regenerative Biomaterial for Heart Valve Tissue Replacement, Page 20
Jahnavi Mudigonda

Poster #24

FcyRIIB as a Novel T Cell Checkpoint in Melanoma, Page 22
Clara Farley

Poster #25

CD28 and CTLA-4 requirements of Primary CD8+ T Cell Responses to a Murine EBV Homolog, Page 23
Rebecca Crepeau

Poster #28

RIP3 Kinase Inhibition Worsens Mortality in Sepsis by Inducing Cellular Apoptosis, an Effect Which is Reversed Following TNF Blockade, Page 24
Caitlin Fitzgerald

Poster #29

Effect of Surgical Margins on Overall Survival in Resectable Pancreatic Cancer Patients, Page 26
Shuo Wang

Poster #32

Pathological Expression of Matrix Metalloproteinases (MMPs) and Their Tissue Inhibitors (TIMPs) in a Volume Overloaded Left Ventricle from Chronic Mitral Valve Regurgitation, Page 28
Daniella Corporan

Poster #33

The Structure and Overall Thickness Changes of the Anterior and Posterior Mitral Valve Leaflets After Undersizing Mitral Annuloplasty to Repair Ischemic Mitral Regurgitation, Page 30
Alicja Sielicka

Poster #42

Recipient IFNAR1 Signaling Supports Costimulation Independent Rejection by Promoting T cell Activation, Page 32
Dave Mathews

Posters – Clinical Science

Poster #5

Publication Patterns and the Impact of Self-Citation Among Minimally Invasive Surgery Fellowships, Page 34
Fadi Balla

Poster #17

Predicting Pathologic Complete Response to Neoadjuvant Chemotherapy in Triple Negative Breast Cancer, Page 35
Julia Saltalamacchia

Poster #19

Caution! Increased Acute Kidney Injury in Enhanced Recovery After Surgery (ERAS) Protocols, Page 37
Crystal Koerner

Poster #20

Transplantation versus Resection for Hilar Cholangiocarcinoma: An Argument for Shifting Treatment Paradigms for Resectable Disease, Page 39
Cecilia Ethun

Poster #34

Validation of the Emergency General Surgery Frailty Index in Patients with Burn Injuries, Page 41
Daniel Maxwell

Poster #39

Factors Associated with Primary Versus Secondary Anastomosis in Intestinal Atresia, Page 43
Margot Hillyer

Poster #44

Increased BMI Is Associated with More Advanced Stage at Presentation and Negative BRAF Mutation Status in Cutaneous Melanoma Patients, Page 44
Constance Shreckengost

Poster #46

Racial/Ethnic Disparities in Living Donor Kidney Transplantation Before and After the New National Kidney Allocation System, Page 45
Xingyu Zhang

Poster #51

Can a Fitbit With Reminder Alarms Motivate Patients to Increase Postoperative Ambulation? A Randomized Control Trial, Page 46
Giacomo Waller

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