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Faculty Profile

Tom Pearson, MD, DPhil

Thomas C. Pearson, MD, DPhil

Livingston Professor of Surgery, Department of Surgery, Emory University School of Medicine

Executive Director, Emory Transplant Center

Director, Kidney Transplant Program, Emory University

Co-Director, Kidney/Pancreas Transplant Program, Emory University

Affiliate Scientist, Yerkes Primate Research Center

Email

tpearso@emory.edu

Telephone

404.727.8464

Certification

American Board of Surgery

Year Joined Emory as a Faculty Member

1991

Bio-Summary

Dr. Pearson and his long-time collaborator Dr. Chris Larsen played a pivotal role in developing the class of immunosuppressive drugs known as costimulation blockers. In 1996, Dr. Larsen, Dr. Pearson, and others published an article in Nature that provided evidence that blocking one of the immune signals required for organ rejection (costimulatory blockage) at the time of transplantation promoted long-term survival of organ allografts in rodents. This finding was rapidly translated to primates at the Yerkes National Primate Research Center and later to humans.

In March 2010, Dr. Pearson, Dr. Larsen, and their colleagues published the data from two international phase III clinical trials of belatacept in the American Journal of Transplantation, concluding that the then-experimental drug could prevent graft rejection in kidney transplant recipients while better preserving kidney function and maintaining lower blood pressure and cholesterol when compared to standard immunosuppressive medications. In June 2011, the FDA approved belatacept in the form of the drug Nulojix for the prevention of graft rejection after kidney transplants. The drug is now being tested in clinical trials for kidney transplant, liver transplant, and pancreatic islet transplant.

In addition to being an eminent scientist, Dr. Pearson is also a highly accomplished transplant surgeon and has been involved in such milestones as the performance of Georgia's first islet transplant.

Publications

Dr. Pearson's publications in Dr. Pearson's publications in PubMed

Affiliations

Medical School

Postgraduate Training

Honors and Awards

Editorships and Editorial Boards

Current Organizational Memberships

Clinical Specialties

Research Interests

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