– Assistant Professor, Division of Cardiothoracic Surgery, Emory University (Primary)
– Assistant Professor, Department of Biomedical Engineering, Georgia Institute of Technology (Secondary)
– Principal Investigator, Structural Heart Disease Research and Innovation Lab
An engineer by training, Dr. Padala is currently focused on studying the biomechanics and mechanobiology of heart valve disease and heart failure. He received his BS in mechanical engineering from Osmania University in India in 2004, and an MS in mechanical engineering and PhD in bioengineering from Georgia Tech in 2010. Since joining Emory and establishing his independent laboratory in 2010, his focus has been on studying in-vivo heart valve and cardiac mechanics in pre-clinical models. In 2012, he spent one year at Imperial College London on a Leducq Fondation Career Development Award. He trained under Prof. Sir. Magdi Yacoub, a pioneer in cardiac transplantation and heart valve tissue engineering.
Dr. Padala's current research interests:
Basic Science: With the objective of discovering the optimal timing of heart valve repair/replacement, Dr. Padala is studying the impact of mitral valve and tricuspid valve regurgitation on structural and functional remodeling of the heart. This work was initially funded by a Leducq Foundation Career Development Award received by Dr. Padala in 2011 that lasted until 2014. Current funding is provided by a Scientist Development Grant he received from the American Heart Association (2014-2018).
Clinical Science: By studying the inadequacies of existing repair methods, Dr. Padala is working to develop new techniques to repair the mitral and tricuspid valves and the injured left ventricle associated with these valve diseases. Funding has been provided by the Carlyle Fraser Heart Center (2012-2015).
Innovations: While essential, the process of moving new concepts from the lab to the patient can be protracted and iterative. Dr. Padala's lab is dedicated to translating scientific concepts into patents and prototypes and is conducting the pre-clinical work required to demonstrate the safety and efficacy of the lab's innovations. This work is funded by an NIH STTR grant (2012-2014), the Georgia Research Alliance (2012-2015), and the Wallace Coulter Foundation (2011-2013). Dr. Padala received the Innovation of the Year award from the Emory Office of Technology Transfer in 2011 for achievements in this area.
Structural Heart Disease Research and Innovation Laboratory, Emory University School of Medicine
Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology
Research Fellowship, Imperial College London, 2012
PhD in Bioengineering, Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, 2010
MS in Mechanical Engineering, Georgia Institute of Technology, 2008
BS in Mechanical Engineering, Osmania University, India, 2004
William W. Parmley Young Author Achievement Award (recognizes outstanding papers published in the Journal of the American College of Cardiology by primary authors who are young investigators), JACC, 2015
Scientist Development Grant, American Heart Association, 2014
Leducq Foundation Career Development Award, 2012
Gandy Diaz Teaching Fellowship, Georgia Institute of Technology, 2009
American Heart Association Pre-Doctoral Fellowship, 2008
American Heart Association
Biomedical Engineering Society
Society of Heart Valve Disease
Mechanisms of mitral and tricuspid valve disease
Heart chamber remodeling in valve disease
Modulating myocardial mechanics to decelerate heart failure
3D echo and MRI imaging to map cardiac and valve mechanics
New techniques for valve and cardiac repair
Transcatheter heart valve repair and replacement
Multi-modality imaging to guide beating heart valve repair